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NUCALA is an add-on, prescription maintenance treatment for patients 6 and older with severe eosinophilic asthma. NUCALA is not used to treat sudden breathing problems.
ONSCREEN TEXT: IMPORTANT SAFETY INFORMATION
Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA. Please see complete Prescribing Information, including Patient Information, at NUCALA.com.
NARRATOR: Remember to watch the complete video to see additional safety information.
ONSCREEN TEXT: Angie Sttafford, VA
ANGIE: I am definitely a go getter.
Angie is a real patient who was taking NUCALA at the time of filming. GSK paid for her time and expenses to share her unique experiences. Results may vary.
ANGIE: I’m a mom. I’m a wife. I’m also a swim and dive coach. Being around pools and water is really a big part of who I am.
ANGIE: I noticed my breathing was kind of off when I exercised. You know, I just was feeling like I couldn't get a good breath and it was different than just being out of breath.
ANGIE: One night I was at home, and I just could not breathe. They ended up admitting me in the hospital.
ANGIE: I was on oxygen. I was on breathing treatments.
ANGIE: In those moments when you when, when…[sigh]…man, I tell you. You. You take breathing for granted.
ANGIE: I just couldn’t recover. I would get winded doing things that I could normally do with no problem. Being on the pool deck was horrible. I felt like I couldn’t breathe.
ANGIE: [I] didn’t realize how much coaching was an outlet for me until it wasn’t there.
ANGIE: My family is the most important thing in my life.
MATT: For me, the scariest thing was waking up in the middle of the night and she's having a full-blown asthma attack. I mean it's frightening to wake up and, and see her struggling to, to breathe and struggling to get ahold of an inhaler.
ANGIE: [I] went from rescue inhaler to maintenance inhaler to a round of steroids, to another maintenance inhaler and then another round of steroids. I would feel jittery, I’m gaining weight, and I wasn't getting any better with my breathing.
ANGIE: I said enough. I had lost a piece of myself that I needed to get back. I wasn't afraid to be pushy. I felt like, “is this is going to be the rest of my life?” Because this is unacceptable.
ANGIE: I had all these things going on and all these challenges and it came down to a simple blood test that led to me being diagnosed with severe eosinophilic asthma.
ANGIE: I'm a problem solver. I'm like, “okay, great, we found the problem. Let's get a solution.”
ANGIE: That was when we started talking about a biologic. [Hey guys! You ready?] Since I've been taking NUCALA, I'm back to normal life.
ANGIE: [Press it down] It was great to be back with the kids. [Good! That looked good! Very nice!]
ANGIE: I can get so into the moment that I just forget about whatever is going on around me. It’s awesome.
ANGIE: It's great to be in a place where I don't have to think about my asthma all the time.
ONSCREEN TEXT: Results may vary. Talk to your doctor before stopping any of your medications.
ANGIE: For me, I was able to taper off the oral steroids, and I haven't had to take any oral steroids since I started NUCALA; September of 2020.
ONSCREEN TEXT: Results may vary.
ANGIE: As a family. It's allowed us to be able to do the things that we love to do.
ONSCREEN TEXT: Results may vary.
MATT: Once she got on NUCALA, we saw a big difference.
ANGIE: I carry a much smaller purse now too (laugh) because I don’t have to have that big bag of inhalers.
ONSCREEN TEXT: Results may vary.
ANGIE: The only inhaler I have is my rescue inhaler in the event that something were to trigger an asthma attack.
ONSCREEN TEXT: Results may vary.
ANGIE: NUCALA has given me back what my asthma took away.
ONSCREEN TEXT: Results may vary.
ANGIE: It's allowed me to move closer to living the life that I want to live, and be the person who I want to be. It's a journey…
ANGIE: …and a process. [Oh! All right. Let’s try it again.]
ANGIE: But I'm thankful that I was able to find NUCALA, to go through that process.
ANGIE: But I'm thankful that I was able to find NUCALA, to go through that process.
ONSCREEN TEXT: Approved Use [NARRATOR and ONSCREEN TEXT] NUCALA is an add-on, prescription maintenance treatment for patients 6 and older with severe eosinophilic asthma. NUCALA is not used to treat sudden breathing problems.
ONSCREEN TEXT: Important Safety Information [NARRATOR and ONSCREEN TEXT]Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA. Do not use to treat sudden breathing problems. NUCALA can cause serious side effects, including:
allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your NUCALA injection. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:
Herpes zoster infections that can cause shingles have happened in people who received NUCALA.
Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you:
are taking oral or inhaled corticosteroid medicines. Do not stop taking your other asthma medicines, including your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back.
have a parasitic (helminth) infection.
are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby.
are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first.
are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.
The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and tiredness (fatigue).
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
NARRATOR: Ask your doctor if NUCALA is right for you.
NUCALA is an add-on, prescription maintenance treatment for patients 6 and older with severe eosinophilic asthma. NUCALA is not used to treat sudden breathing problems.
ONSCREEN TEXT: IMPORTANT SAFETY INFORMATION
Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA. Please see complete Prescribing Information, including Patient Information, at NUCALA.com.
NARRATOR: Remember to watch the complete video to see additional safety information.
ONSCREEN TEXT: Life before NUCALA (mepolizumab)
ONSCREEN TEXT: Teri is a real patient who was taking NUCALA at the time of filming. GSK paid for her time and expenses in sharing her unique experiences.
TERI: It just felt like an elephant was sitting on my chest. That was one of the earlier onset signs of struggling to breathe.
TERI: Over the next 7 years from that day, it was a constant struggle… breathing. The congestion, wheezing, asthma attacks. And it just kept progressing. If I wasn’t having an asthma attack, I definitely was always worried about having one. It really was kind of debilitating to me… as a mother, you know, as a wife, as a professional. I felt like I had to turn down a lot of work opportunities because of the problems I had with my breathing. At home it was difficult for me to go to my kids’ soccer games. And I missed a lot of moments in their lives where they would want me to be there… I couldn't be there. My husband and I enjoy dancing. That's how we, you know, connected. That was one of the things that, you know, bring us close together. And unfortunately, we couldn’t do that anymore.
DENNIS: Do you remember that… I think it was Erica’s birthday.
TERI: We were supposed to go dancing with them.
DENNIS: And we were probably about, what, 50 percent into the drive?
TERI: Yep.
DENNIS: And the code word was given, right?
TERI: Yep. “It's hot in here.”
DENNIS: And that was the indication to turn around. Yeah, I used to dread that word, because there were times where you’d end up in the hospital was when that word was given.
TERI: It had gotten to the point where I was going to the ER all the time. It was just like a vicious cycle of steroids, breathing treatments, and other medications that were temporary. It wasn’t solving any problems; it was just giving me a temporary relief. It was pretty frustrating.
ONSCREEN TEXT: Getting Diagnosed
ONSCREEN TEXT: Teri is a real patient who was taking NUCALA at the time of filming. GSK paid for her time and expenses in sharing her unique experiences.
TERI: The turning point was when I was in the parking lot of the ER and didn’t have the breath to walk inside. I had to call 911 from the parking lot. I was sitting there thinking, oh my God, I'm gonna die here in the parking lot… And it was the worst day of my life.
TERI: As soon as they let me go home, I went to see a pulmonologist, and I was literally crying, begging him, “please help me.” My doctor really took the time and listened to me and reviewed my medical history to look for an answer. He told me he thought he knew what was wrong with me. And he explained to me that he thought too many eosinophils may be contributing to my asthma. I had never heard of eosinophils before. I didn't even know that there were different types of asthma. He ran a blood test, and once the results came back, he diagnosed me with…
ONSCREEN TEXT: Severe eosinophilic asthma
TERI: …severe eosinophilic asthma. I think I jumped for joy that day [laughs] to hear the words, “I know what's wrong with you.”
ONSCREEN TEXT: Discovering NUCALA (mepolizumab)
ONSCREEN TEXT: Teri is a real patient who was taking NUCALA at the time of filming. GSK paid for her time and expenses in sharing her unique experiences. Results may vary.
TERI: My doctor told me that being diagnosed with severe eosinophilic asthma meant that I was going to be a candidate for NUCALA. So, he gave me a pamphlet to read about the side effects. He told me about the things that could happen…
ONSCREEN TEXT: Results may vary.
TERI: …like serious allergic reactions, headaches, injection site reactions or back aches and fatigue, among other things, but we decided I would give it a try. He wanted to get me started right away, and he told me it wasn’t for when I have sudden breathing problems, but it was an injection taken…
ONSCREEN TEXT: Every 4 weeks Results may vary.
TERI: …every four weeks, in addition to my inhalers.
ONSCREEN TEXT: Sometimes, serious allergic reactions, including anaphylaxis, can occur hours or days later. NUCALA at home does not take the place of doctor’s visits. Results may vary.
TERI: And then, once I got the injection, I had to sit and wait for about 30 minutes to make sure I didn't have any adverse reaction, which I didn't.
ONSCREEN TEXT: Results may vary.
TERI: I do not like needles at all, but when you've been through years and years of struggling to breathe, and the doctor says that it's delivered by injection, you don't care, you're like, you know what… I'm gonna tough it up and I'll be okay. My personal experience with NUCALA after that first injection…
ONSCREEN TEXT: Studies showed varied improvements in lung function. Results may vary.
TERI: I was doing pretty good… I stopped wheezing; I was breathing a whole lot better.
ONSCREEN TEXT: Talk to your doctor before stopping any of your medications. Results may vary.
TERI: For me, it was a new beginning.
DENNIS: Now, how about that trip we took after you got on the medication?
TERI: Oh, huh- huh, yep!
TERI: When your sister’s wedding in Jamaica? We had a good time.
DENNIS: Yeah. Couldn't keep you off the beach. We were able to enjoy it. It was the first vacation we had in years.
TERI: I'm grateful for that. You know, I was so overjoyed and with my family, we’ve been traveling more, going on more vacations, fishing, and gardening. I’m very grateful. Very grateful.
ONSCREEN TEXT: NUCALA (mepolizumab) at home
ONSCREEN TEXT: Teri is a real patient who was taking NUCALA at the time of filming. GSK paid for her time and expenses in sharing her unique experiences. Results may vary.
TERI: In the beginning, taking two hours to go to my doctor's office to get my NUCALA injection, you know, I was happy to do it because it helped my breathing, it helped control my asthma, so that wasn't an issue for me.
ONSCREEN TEXT: Autoinjector for patients 12 and older. Results may vary.
TERI: But learning about the NUCALA Autoinjector, I was so excited because having that time back and having it delivered to my home where I could do it in the comfort of my home. I was super excited about that.
ONSCREEN TEXT: Results may vary.
TERI: I don't have to leave work; I don't have to worry about scheduling an appointment.
ONSCREEN TEXT: Your healthcare provider will give you information you need to inject properly and about monitoring for any allergic reactions. Sometimes, serious allergic reactions, including anaphylaxis, can occur hours or days later. NUCALA at home does not take the place of doctor’s visits. Results may vary.
TERI: And I'm in control of it. Not being able to see the needle is wonderful because I hate needles, but the Autoinjector is so easy…
ONSCREEN TEXT: Read the full Instructions for Use that comes with NUCALA for instructions about the right way to give your injections at home. Sometimes, serious allergic reactions, including anaphylaxis, can occur hours or days later. NUCALA at home does not take the place of doctor’s visits.
TERI: …you just pop the top, and follow the instructions of course, and I inject it into my thigh. It takes like, 20 seconds and you're done.
ONSCREEN TEXT: Autoinjector for patients 12 and older. Results may vary.
TERI: I know I gotta take it every four weeks, I follow the instructions …
ONSCREEN TEXT: It doesn’t inconvenience my life Autoinjector for patients 12 and older. Results may vary.
TERI: It's easy, it doesn't inconvenience my life at all.
ONSCREEN TEXT: Life with NUCALA (mepolizumab)
ONSCREEN TEXT: Teri is a real patient who was taking NUCALA at the time of filming. GSK paid for her time and expenses in sharing her unique experiences. Talk to your doctor before stopping any of your medications. Results may vary.
TERI: Since I started NUCALA, I’ve been able to taper off oral steroids, had no asthma attacks, and no asthma-related ER visits. I'm not using my rescue inhaler, every 5 to 10 minutes anymore.
ONSCREEN TEXT: Talk to your doctor before stopping any of your medications. Results may vary.
TERI: I haven't used my nebulizer. And I’m not as worried about having an asthma attack.
ONSCREEN TEXT: My NuNormal is living life Results may vary.
TERI: My new normal is living life!
ONSCREEN TEXT: Results may vary.
TERI: At home, now, I’m the mother that I want to be, that my kids need me to be. My family is really happy [laughs] that I’m better because not only do I get to live my life, they get to have me do things with them and not have to worry about… Is Mom gonna be okay, or is my wife gonna be okay, because now we're just enjoying one another, experiencing life together now. At work, I’m not as concerned about missing meetings because of my breathing issues, like wheezing or getting short of breath during conference calls. I’m enjoying a different professional life now.
ONSCREEN TEXT: Teri’s ADVICE
ONSCREEN TEXT: Teri is a real patient who was taking NUCALA at the time of filming. GSK paid for her time and expenses in sharing her unique experiences. Results may vary.
TERI: I remember feeling like no one understood what I was going through. And I want people to know that they are not alone. There are different kinds of asthma, and you should talk to your doctor if you’re having symptoms.
ONSCREEN TEXT: Ask for a simple blood test
TERI: Ask for a simple blood test to check your eosinophil levels and if…
ONSCREEN TEXT: NUCALA could be an option
TERI: … NUCALA could be an option for you.
ONSCREEN TEXT: Results may vary.
TERI: For me personally, my asthma is better controlled and I’m on a treatment plan that’s right for me. When I look back, I realize that first injection was the beginning of a new chapter for me. And now I’ve been taking NUCALA for a couple years, and I’m just so grateful. I even sent my doctor an email saying, “Thank you so much. You just don’t know how much of a difference you’ve made.” The Teri before NUCALA and the Teri with NUCALA… two different versions of-of-of who I am.
ONSCREEN TEXT: [NUCALA logo: NUCALA (mepolizumab) Injection 100 mg/mL] I am the best version of me Results may vary.
TERI: I am the best version of who I’m supposed to be, who I am. The best version of Teri.
ONSCREEN TEXT: Important Safety Information
NARRATOR: NUCALA is an add-on, prescription maintenance treatment for patients 6 and older with severe eosinophilic asthma. NUCALA is not used to treat sudden breathing problems. Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA. Do not use to treat sudden breathing problems.
NUCALA can cause serious side effects, including: Allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your NUCALA injection. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction: swelling of your face, mouth, and tongue, breathing problems, fainting, dizziness, feeling lightheaded (low blood pressure), rash, hives.
Herpes zoster infections that can cause shingles have happened in people who have received NUCALA.
Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you: Are taking oral or inhaled corticosteroid medicines. Do not stop taking your other asthma medicines, including your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back. Have a parasitic (helminth) infection. Are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby. A pregnancy registry for women who receive NUCALA while pregnant collects information about the health of you and your baby. You can talk to your healthcare provider about how to take part in this registry or you can get more information and register by calling 1-877-311-8972 or visit www.mothertobaby.org/asthma. Are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first. Are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.
The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and tiredness (fatigue).
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Ask your doctor if NUCALA at-home administration is right for you.
ONSCREEN TEXT: Approved Use NUCALA is an add-on, prescription maintenance treatment for patients 6 and older with severe eosinophilic asthma. NUCALA is not used to treat sudden breathing problems.
Important Safety Information Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA. Do not use to treat sudden breathing problems.
NUCALA can cause serious side effects, including:
allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your NUCALA injection. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:
Herpes zoster infections that can cause shingles have happened in people who received NUCALA.
Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you:
are taking oral or inhaled corticosteroid medicines. Do not stop taking your other asthma medicines, including your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back.
have a parasitic (helminth) infection.
are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby.
A pregnancy registry for women who receive NUCALA while pregnant collects information about the health of you and your baby. You can talk to your healthcare provider about how to take part in this registry or you can get more information and register by calling 1-877-311-8972 or visit www.mothertobaby.org/asthma.
are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first.
are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.
The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and tiredness (fatigue).
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
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