What is NUCALA? | NUCALA (mepolizumab)

NUCALA is a different kind of treatment for severe asthma

It’s an injection you take every 4 weeks in addition to your current asthma medicines. You can get your NUCALA injection in your doctor’s office or take it at home.

Check out NUCALA’s stats

See how NUCALA performed in several studies with patients who added NUCALA to their current asthma medicines compared to those who did not.

Majority of patients reduced or eliminated their oral steroid use
while maintaining asthma control*

fewer asthma
attacks^†
NUCALA patients had 0.83 asthma attacks/year vs 1.74 in patients taking a placebo

fewer asthma attacks in patients with higher eosinophil levels^†‡
NUCALA patients with high eosinophil levels in their blood (≥500 cells/mcL) had 0.54 asthma attacks/year vs 2.11 in patients taking a placebo

fewer severe asthma attacks requiring hospital or ER visits^‡
NUCALA patients had 0.08 asthma attacks/year requiring hospitalization/ER visits vs 0.20 in patients taking a placebo

Patients also stated they had a better health-related quality of life after taking NUCALA.^§

Results may vary.

*In a clinical study, 64% of NUCALA patients reduced or eliminated their daily oral steroid use vs 44% of patients not taking NUCALA. The study showed 14% of NUCALA patients eliminated daily steroid use vs 8% of patients not taking NUCALA. Based on limits of the analysis, results are descriptive and your experience may differ.

^†In a clinical study of patients with ≥150 cells/mcL blood eosinophil (a type of white blood cell).

^‡A trend of greater reduction in asthma attacks in patients with increasing blood eosinophil levels, including a 75% reduction in patients with higher eosinophil levels (≥500 cells/mcL). Based on limits of the analysis, results are descriptive and your experience may differ.

^§Based on the limits of the study, the results are descriptive, and your experience may or may not be the same.

Have you asked your doctor about NUCALA?

So, you’ve already started NUCALA

Don’t forget to sign up for MyNUCALA for information, resources, and support to keep you on track.

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So, you’re still thinking about NUCALA

It’s important to be open and honest with your doctor about your asthma to make sure you’re on the treatment plan that’s right for you.

Get the conversation started

So, you’re ready to ask about NUCALA

Download the doctor discussion guide to keep the conversation on track.

Wondering if NUCALA could be right for you?

Watch real stories of patient experiences with NUCALA.

See the stories

How can NUCALA help severe asthma?

NUCALA may decrease airway inflammation that can cause severe asthma attacks. It works by targeting eosinophils, a key source of asthma inflammation, so it treats more than just your symptoms of severe asthma. Find out more about how NUCALA works.

The mechanism of action of NUCALA is not fully understood.

How do I know if NUCALA is an option for me?

Your doctor can give you blood testing that measures your eosinophil count. In clinical studies, the eosinophil blood test helped identify patients whose asthma was more likely to respond to treatment with NUCALA.

Your blood test results may help your doctor diagnose you with severe eosinophilic asthma. They may recommend adding NUCALA to your asthma treatment plan.

At home. On your time.

With the NUCALA Autoinjector, you can self-inject right at home once a month.*

Autoinjector for patients aged 12+
*Every 4 weeks.

Learn about the Autoinjector

Interested in NUCALA? Here’s what to do next

If you’re wondering whether NUCALA can help prevent your severe asthma attacks, start by talking to your doctor. We’ll help you get started:

Tell your doctor everything you’re doing to manage your severe asthma, and talk about how your asthma is affecting your life.

Ask your doctor if adding NUCALA to your current asthma treatment could help improve your severe asthma.

Ask for blood testing to help see if you have severe eosinophilic asthma.

Ready to talk to your doctor?

The doctor discussion guide can keep the conversation on track.

Download the Guide

Need help finding a specialist?

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Why NUCALA?