Your first EGPA treatment

Support and information to keep your treatment journey on track

Your doctor has prescribed NUCALA for you.

Your doctor will review your blood eosinophil count, other test results, symptoms, and current medicines. It is important to tell your doctor about all of your medicines and medical conditions before receiving NUCALA.

You should know that filling your prescription will be a little different from what you may be used to.

What’s next?

Before your prescription can be filled, your doctor or specialty pharmacy will work through the approval process with your insurance company. During this process, your doctor, specialty pharmacy, or insurance company may need to call you to collect important information or payment. Be on the lookout for a call from your specialty pharmacy (you may not recognize the number), and be sure to respond to any voicemails they leave. Not doing so could delay your treatment. You can read more about this part of the process and learn about programs that can help on our insurance info page.

After you’ve been approved by your insurance company to receive NUCALA, it will be shipped directly to your doctor’s office or your home, depending on where you will take your injections. Keep in mind that this entire process takes time, so it may take several weeks to receive your first treatment of NUCALA.

NOTE: If you don’t have insurance coverage, you may qualify for our Patient Assistance Program.

Finding support

At each step in the process, various members of the support team will be available to answer your NUCALA questions. Your doctor’s office, Gateway to NUCALA (if services are requested), your insurance company, and your specialty pharmacy will work together to help you get your medication. Our patient support program, called MyNUCALA, also offers a Nurse Support Line to answer any other questions you may have.

Your doctor’s office

Prescribes NUCALA and works with insurance. If you are taking NUCALA at your doctor’s office, your doctor also schedules your injection appointments.

Gateway to NUCALA

If requested, this service provided by GSK is designed to help you with insurance questions and, if you are eligible, can help you enroll in the NUCALA Copay Program.

The NUCALA Copay Program may help eligible commercially insured patients with their out-of-pocket costs for NUCALA.

Eligibility restrictions and program maximums apply. Visit www.GSKCopayPrograms.com for complete Program Terms and Conditions.

Nurse Support Line

Nurses are available to help answer your questions about NUCALA, Monday–Friday, 8 AM–8 PM ET at 844-4-NUCALA (844-468-2252). You can also sign up for the MyNUCALA Patient Support Program to receive more resources for your treatment journey.

To avoid any delays in your treatment with NUCALA, make sure to return any calls you receive from your doctor, Gateway to NUCALA representatives, and your specialty pharmacy.

What to expect during your first treatment

At your doctor’s office
  • Your doctor will prepare your injections
  • You will receive your injections just underneath your skin (subcutaneously)
  • After your injections you may be asked to stay in the office so your doctor can monitor you for serious allergic reactions
  • Sometimes serious allergic reactions, including anaphylaxis, can occur hours or days after administering NUCALA. See risks and side effects
At home
  • NUCALA can also be taken at home with the Autoinjector. Your doctor will provide information on how to properly inject at home plus provide education about monitoring for serious allergic reactions. Sometimes serious allergic reactions, including anaphylaxis, can occur hours or days after administering NUCALA
  • You will inject yourself underneath your skin (subcutaneously). Instructional videos, the full Instructions for Use, and other support for self-injection are available

Questions you may have

Whether you’ve already begun your treatment with NUCALA or just received a prescription for it, you probably have some questions. Most patients do. You’ll want to talk to your doctor about how NUCALA works and any other concerns you might have. In the meantime, we have some answers to the initial questions you may have.

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  • Is remission possible with NUCALA?

    Compared to placebo, more patients taking NUCALA were in remission within the first 6 months and continued to stay in remission for the rest of the 1-year study.

    By remission, we mean that patients have no active vasculitis and a prednisone or prednisolone dose less than or equal to 4 mg per day.

    Was this helpful?

    Yes, it was helpful.
    No, it was not helpful.

  • Will I relapse?

    While you may still experience a relapse, the time between relapses could be longer with NUCALA.

    For patients receiving NUCALA in the study, all types of relapses (vasculitic, asthma, and sinonasal) occurred at a lower rate. In addition, their annual relapses were reduced by half.

    By relapse, we mean worsening of symptoms that required an increase in steroid dose, and/or increase in dose or start of immunosuppressants, and/or hospitalization.

    Was this helpful?

    Yes, it was helpful.
    No, it was not helpful.

  • Will my doctor be able to reduce my oral steroid dose?

    Patients who received NUCALA had a lower average oral steroid dose by the end of the 1-year study.

    Almost half the patients who received NUCALA had their steroid dose reduced to 4 mg or less per day.

    Even better, the doctor was able to stop oral steroid use altogether for 1 out of every 5 patients.

    Was this helpful?

    Yes, it was helpful.
    No, it was not helpful.

You may or may not have the same experience while taking NUCALA. Start the conversation with a Doctor Discussion Guide.

What NUCALA can do

During a 1-year clinical study, more patients who added NUCALA to their EGPA treatment experienced:

Longer time in remission*

Fewer relapses†

Lower dose of oral steroids

Results may vary.

*"Complete remission" was defined as no active vasculitis and a prednisone or prednisolone dose less than or equal to 4 mg per day.
†"Relapse" was defined as worsening symptoms that required increased steroid dose, and/or increase in dose or start of immunosuppressants, and/or hospitalizations.

A few things to keep in mind as you continue your treatment with NUCALA

  • Don’t make any changes in your medicines without first consulting your doctor
  • If you take NUCALA at your doctor’s office and miss an injection appointment for any reason, talk to your doctor about getting back on track as soon as possible
  • If you take NUCALA at home and miss a dose (300 mg, administered as 3 separate 100-mg injections), you or your caregiver should inject your dose of NUCALA as soon as you remember. Then, continue (resume) your injections on your regular dosing schedule. If you do not notice that you have missed a dose until it is already time for your next scheduled dose, just inject the next scheduled dose as planned. If you are not sure what to do, ask your doctor, pharmacist, or nurse

Thinking about starting NUCALA?

MyNUCALA can support you along the way.

Sign up now